Active Ingredients: Azithromycin
Developmental toxicity studies with azithromycin in rats, mice, and rabbits showed no drug-induced fetal malformations at doses up to 3, and 1 times, respectively, an adult human daily dose of 600 mg based on body surface area.
The estimated background risk of major birth defects and miscarriage for the indicated populations is unknown. All pregnancies have a background risk of birth defect, loss, or other adverse outcomes.
In the U. Data Human Data Available data from published observational studies, case series, and case reports over several decades do not suggest an increased risk for major birth defects, miscarriage, or adverse maternal or fetal outcomes with azithromycin use in pregnant women.
Limitations of these data include the lack of randomization and inability to control for confounders such as underlying maternal disease and maternal use of concomitant medications. Based on body surface area, this dose is approximately 3 rats and 2 mice times an adult human daily dose of 600 mg.
Maternal toxicity reduced food consumption and body weight gain; increased stress at parturition was observed at the higher dose.
Lactation Risk Summary Azithromycin is present in human milk see Data. There are no available data on the effects of azithromycin on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for Zithromax and any potential adverse effects on the breastfed infant from Zithromax or from the underlying maternal condition.
Clinical Considerations Advise women to monitor the breastfed infant for diarrhea, vomiting, or rash.
Data Azithromycin breastmilk concentrations were measured in 20 women after receiving a single 2 g oral dose of azithromycin during labor.
Breastmilk samples collected on days 3 and 6 postpartum as well as 2 and 4 weeks postpartum revealed the presence of azithromycin in breastmilk up to 4 weeks after dosing. Breastmilk colostrum samples obtained between 12 and 48 hours after dosing revealed that azithromycin persisted in breastmilk up to 48 hours.
Safety data are available for 72 children 5 months to 18 years of age mean 7 years who received azithromycin for treatment of opportunistic infections.
Adverse reactions were similar to those observed in the adult population, most of which involved the gastrointestinal tract.Strengths: 250 mg, 500 mg, 600 mg Brand: Zithromax Strengths: 250 mg, 500 mg For bronchitis Adult dosage ages 18 years and older Typical dosage is 500 mg once per day for 3 days.
Treatment-related reversible hearing impairment in children was observed in 4 subjects 5. Two 2.
A third child discontinued due to a laboratory abnormality eosinophilia. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.
Zithromax for oral suspension 1 gram single-dose packets contain 37. These patients were treated for a variety of opportunistic infections, including MAC. Never try to catch up by taking two doses at once.
This could result in dangerous side effects. How to tell if the drug is working: Your infection should go away. In case of overdose If you take too much azithromycin, you could have dangerous levels of the drug in your body.
Important considerations for taking azithromycin General You can take this drug with or without food. Refills A prescription for this medication is refillable.