Active Ingredients: Norfloxacin
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Twenty participants did not complete the 5-day study regimens absence from work, for 15 participants; subject quit job, for 4; and intolerability of side effects of norfloxacin, for 1.
As a consequence, the numbers of trial participants on assessment days 7, 30, 60, and 90 were 257, 244, 239, and 230, respectively.
There were no statistically significant differences between the 3 treatment groups with regard to baseline characteristics table 1.
The bacteriological findings serotype distribution and antimicrobial susceptibility pattern of NTS isolates from pretreatment cultures, as well as proportions of participants with coinfection were comparable among the 3 treatment groups.
The Salmonella isolates recovered from the participants at enrollment were of 42 serotypes, the 2 most common of which were Salmonella enterica serotype Anatum and S. Table 1 Baseline characteristics of participants in a trial of norfloxacin and azithromycin for treatment of nontyphoidal salmonellae carriage, according to treatment group.
Table 2 Bacteriological findings of pretreatment rectal swab cultures for the 3 treatment groups.
Table 2 Open in new tab Download slide Bacteriological findings of pretreatment rectal swab cultures for the 3 treatment groups.
The results of cultures of rectal swabs obtained from the participants on assessment days 7, 30, 60, and 90 are shown in table 3.
Table 3 Proportions of trial participants with positive results of nontyphoidal Salmonella cultures, by treatment group, on each of the 5 bacteriological assessment days.
Table 3 Open in new tab Download slide Proportions of trial participants with positive results of nontyphoidal Salmonella cultures, by treatment group, on each of the 5 bacteriological assessment days.
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