Active Ingredients: Gabapentin
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Abstract The current work is targeted to review the risks of gabapentin misuse, its potential interactions with other drugs, side effects and use contraindications. This review consists of a total of 99 biographical references from the year 1983 to.
It included animal studies, clinical studies, case studies and reviews related to gabapentin misuse, potential interactions, side effects and use contraindications.
The search terms were gabapentin, anticonvulsant and antiepileptic. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. Finally, reports in general contraindicate the use of gabapentin in conditions such as myasthenia gravis and myoclonus.
Keywords: gabapentin, misuse, interactions, contraindications, side effects Introduction Methodological procedure of the review The current review consists of a total of 99 biographical references from the year 1983 to.
It included animal studies, clinical studies, case studies and reviews related to gabapentin misuse, interactions, toxicology and pharmacological description of gabapentin.
The search terms included were gabapentin, anticonvulsant and antiepileptic. Basic information of gabapentin Gabapentin is a pharmaceutical drug that has a white solid small crystals physical appearance.
The molecular formula of gabapentin is C 9 H 17 NO 2, and it has a formula weight of 171. Commercially, gabapentin can be obtained in the forms of capsules or tablets of diverse doses capsules: 100, 300 and 400 mg; tablets: 300, 600 and 800 mg; webpage of the United States National Library of Medicine.
Gabapentin has various pharmacokinetic and pharmacodynamic properties.
The main purpose of the current work is to present an updated review about the problems related to gabapentin misuse, side effects, interactions with other drugs and use contraindications.
Problems related to misuse, abuse or dependence on gabapentin Case clinical and large group studies suggest that gabapentin can be abused and induce health problems.
In addition, the participants reported the use of gabapentin an average of 25 days out of the 30 previous days. Hence, there are limitations for generalizing these findings to a broader population because of the small sample size and the special group reported inmates.
A limitation of this study was the lack of validation of the questionnaire employed.
Another study evaluated the misuse of gabapentin based on the analysis of information posted in web pages.