Active Ingredients: Gabapentin
In a large meta-analysis of adults with sleep disturbances by Liu et al, 25 gabapentin demonstrated efficacy over placebo in 5 out of 7 composite end points.
However, tolerability was comparatively lower than placebo and included studies only assessed sleep changes secondary to other indications such as neuropathic pain and RLS. Shanthanna et al 26 conducted a review of randomized controlled trials of at least 3 months duration for gabapentinoids and chronic lower back pain.
A total of 8 studies were included in the systematic review and 6 studies for meta-analysis evaluating pain relief as the primary outcomes.
Call your doctor if you become pregnant while taking this drug. This registry tracks the effects of anti-seizure drugs on pregnancy.
Information can be found at aedpregnancyregistry. Tell your doctor if you are breastfeeding.
You should decide together if you should stop taking this drug or stop breastfeeding. For children: Gabapentin has not been studied in children for the management of postherpetic neuralgia.
It should not be used in people younger than 18 years.
This drug should not be used to treat partial seizures in children younger than 3 years. If you or someone you know is considering suicide, get help from a crisis or suicide prevention hotline.
Gabapentin oral capsule is used for short-term or long-term treatment. With this condition, short or long seizures occur for 30 minutes or more.
However, the need often exists for a higher-concentration oral liquid, and if tablets or capsules are used as the drug source, a suspension will result. Both formulations had the same stability and beyond-use dates, so the alternative formula could be used if desired.
It has a pH of approximately 4. It contains purified water, microcrystalline cellulose, sodium carboxymethylcellulose, xanthan gum, carrageenan, sodium phosphate, and citric acid as buffering agents, simethicone as an antifoaming agent, and potassium sorbate and methylparaben as preservatives.
It is flavored with a citrus-berry flavor blend and contains glycerin and sorbitol to prevent cap lock, a problem associated with many syrups.