Active Ingredients: Gabapentin
So far gabapentin, for instance, is only approved for the management of partial seizures and neuropathic pain associated either with diabetes peripheral neuropathy or herpes zoster infections postherpetic neuralgia.
Data include demographic characteristics as well as information on in- and outpatient diagnoses, treatments and procedures, outpatient prescriptions, and care level.
Prescription data are limited to drugs reimbursed by the SHI.
Only drugs prescribed by a physician and dispensed by a pharmacy are included in the data. Since this study was based on anonymous data, patient-informed consent was not required by German regulations.
Based on inpatient and confirmed outpatient diagnoses, comorbidity and potential indications for gabapentinoid use were analyzed in the quarter of the index prescription and the preceding quarter.
We considered epilepsy and neuropathic pain as on-label indications for both drugs and additionally anxiety disorders for pregabalin.
Virender K. Sharma, Long Chen, and Radek Zboril.
Rathod, and Kumudini V. Rolf U.
Quantum-Chemical Study of the Reaction Mechanism. The Journal of Physical Chemistry A.
Nichola M. Muthaiyan Kumar and Rengasamy Tamilarasan.
Chemical Reviews. Longzhu Q.
Shen, Evan S. Methods: We analyzed data from a large German statutory health insurance database. We determined the number and proportion of common indications for on- and off-label prescriptions, the most frequent co-medications, and the characteristics of patients and prescribers.
Results: Of 127,277 residents, 9539 7. Median age of gabapentinoid initiators was 84 years 78. In these users, on-label prescribing was found in 57.